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Pioglitazone

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Pioglitazone
Drug
Wikipedia articleDbpedia source
Pioglitazone (Actos) is a prescription drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. Actos was the tenth-best selling drug in the U.S. in 2008, with sales exceeding $2.4 billion. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes has not yielded statistically significant results. Its cardiovascular safety profile compares favorably with rosiglitazone (Avandia), which was withdrawn after concerns about an increased risk of cardiac events. Pioglitazone has been found to be associated with bladder cancer and has been withdrawn in France, Canada, Australia, New Zealand, India and Japan.
Pioglitazone
Atc prefix A10
Atc suffix BG03
Chebi 8228
Drugbank DB01132
Fda unii code X4OV71U42S
Iupac name (RS)-5-(4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl)thiazolidine-2,4-dione

Conceptual map: Pioglitazone

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Fecha publicación: 15.4.2015

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